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I did some testing with Microsoft iSCSI with multipath (MPIO) versus having bonded adapters with line down detection. It appears that after the line is dropped, micosoft MPIO takes up to 60 seconds of "freezing" before failing over the connection. This is unacceptable in production environment. So I tried to deploy HP ProLiant server with HP drivers running in full round robin bonding with 3 second line down detection time and on the other end I ran bonding module on Linux kernel with mii link test of 100 ms.
The results were somewhat surprising - when link went down, both ends detected the failure within 5 seconds as expected with very little "freezing" time. If you are deploying iSCSI initiator and linux based target you will be better off if you bond your cards to get both much higher failure detection speed as well as increased overall throughput in some cases. If you run MPIO in failure detection mode, essentially only one line is running and second connection is to be used as backup. When running MPIO in round robin fashion, the speed improves, however, still the freezing occurs. When line is maintained by hardware, the failover happens quickly. Lost packets are retransmitted also within short period of time and your system does not freeze nearly as much as it does with MPIO. Bottom line - ditch MPIO, the software based multipath, for hardware and driver based detection - you will get better results
permanent link to article http://freecash.hogger.net/multipath_mpio_iscsi_from_microsoft_on_server_2008_and_server_2003_vs_path_bonding_with_failure_detection
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